NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Exposure to common insecticides associated with risk of death

People with higher exposures to common insecticides called pyrethroids had an increased risk of death in the years following the measurements.

Understanding allergic reactions to skin care products

A laboratory study gave new insight into how skin creams, cosmetics, and fragrances may cause immune responses that lead to rashes in some people.

Blood protein signatures change across lifespan

Blood levels of around 400 proteins accurately reflected people’s age and relative health. Such a protein signature might help identify people at greater risk of age-related diseases.

Immune cell metabolism altered in ME/CFS

Scientists found that some immune cells in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce and use energy.

Researchers find cause of new autoinflammatory disease

Researchers found that mutations in a specific gene cause a previously unknown autoinflammatory disease, which they’ve named CRIA syndrome.

2019 Research Highlights - Human Health Advances

NIH accomplishments in disease prevention, diagnosis, and treatment include treatments for the Ebola virus, gene therapy that reverses a rare immune disorder, and a blood test to detect myalgic encephalomyelitis/chronic fatigue syndrome

2019 Research Highlights - Promising Medical Findings

NIH findings with potential for enhancing human health include a way to predict which people at risk for psychosis may progress to full psychosis, insights into recurrent tonsillitis, and a patch to replace damaged retinal cells.