NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Number of steps per day more important than step intensity

Adults who took 8,000 or more steps a day had a reduced risk of death over the following decade than those who only walked 4,000 steps a day.

Dopamine affects how brain decides whether a goal is worth the effort

Researchers found that drugs like Ritalin may work as a study aid by shifting attention, through the brain chemical dopamine, from the challenges of undertaking a difficult mental task to its rewards.

Technique reveals organization of tongue bacteria

Using advanced imaging techniques, researchers revealed how different bacteria live together in communities on the human tongue.

Study suggests new coronavirus may remain on surfaces for days

Scientists found that SARS-CoV-2, the virus that causes COVID-19, can be detected in aerosols for up to three hours and on plastic and stainless steel surfaces for up to three days.

Spinal nerve healing enhanced by boost in cellular energy

Mice engineered to lack a protein that anchors mitochondria in injured nerve cells showed regrowth of those cells after a spinal cord injury.

Insights into skin formation

Researchers discovered how distinct liquid droplets within cells help build the skin’s outer layer. The study may lead to a better understanding of conditions like atopic dermatitis and psoriasis.

Memories involve replay of neural firing patterns

Researchers found that the distinct firing patterns of individual neurons that the brain uses when forming memories are replayed when remembering the experience.