NIH Research Matters

Autoimmunity may be on the rise, based on a study of antinuclear antibodies in blood samples collected nationwide from 1988-2012.

When delivered to mice using microneedles, an experimental vaccine for COVID-19 caused antibody production against the disease within two weeks.

Researchers found that a small cluster of mutations in the NLGN4X gene, which has been linked to autism spectrum disorder, may explain the sex differences tied to the gene.

In experiments in cells and mice, blocking a protein called LRP1 stopped both normal and harmful forms of tau, which are involved in dementias, from spreading between neurons.

A new technique to engrave 3D-printed scaffolds could be used to boost the repair of complex tissues with different types of cells, such as bone and cartilage.

Although diet quality improved modestly for American children and adolescents from 1999 to 2016, more than half still had poor quality diets.

For patients with heart disease, invasive procedures showed similar reductions in the risk of heart attack and death to medication and lifestyle changes alone.