NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Lower wealth linked with faster physical and mental aging

Older adults with less wealth had sharper declines in many measures of physical and mental health than those with more wealth.

Gut bacteria influence behavior in worms

Specific gut bacteria influenced eating decisions in worms by affecting their response to odors. The findings give insight into one way gut microbes may affect behavior.

Unique genomic features of fatal coronaviruses

A genomic analysis may help explain why some coronaviruses, like SARS-CoV-2, can be deadly, while others cause only mild illness.

Signature of virus exposure may help detect liver cancer

A blood test that measures people’s exposure to different viruses identified those who later developed liver cancer. The test could play an important role in improving outcomes for patients.

Universal mosquito vaccine tested

A small trial showed that a vaccine designed to provide broad protection against mosquito-borne diseases is safe and causes a strong immune response in healthy volunteers.

Gut bacteria may contribute to abnormal blood vessel formation

People with abnormal clusters of blood vessels in the brain called cavernous angiomas had differences in their gut bacteria. The findings could help lead to new diagnostic tests and treatments.

Hairy human skin generated from stem cells

Researchers created hair-growing skin from human stem cells and successfully grafted it to mice.