NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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How anesthetics and benzodiazepine affect the brain differently

Scientists identified how anesthetic and benzodiazepine drugs change a brain receptor’s shape. The findings suggest ways to design more tailored anesthetic drugs.

Computer-designed proteins may protect against coronavirus

Researchers designed “miniproteins” that bound tightly to the SARS-CoV-2 spike protein and prevented the virus from infecting human cells in the lab.

Poor immune response impairs diabetic wound healing

Researchers found that diabetic foot ulcers don’t recruit the immune cells necessary for normal wound healing. The study also identified potential targets for future therapies.

High blood pressure awareness and treatment declining

After increasing between 1999 and 2014, both awareness and treatment of high blood pressure dropped among adults in the U.S.

Biomarkers predict concussion recovery time

Researchers identified two blood proteins that are linked to length of time needed by college athletes to return to play following a sports-related concussion.

Bacteria therapy improves eczema in children

An experimental probiotic treatment for eczema safely improved symptoms and increased quality of life for children 3 to 16 years of age.

How high fructose intake may trigger fatty liver disease

A study suggested that consuming high amounts of fructose may promote non-alcoholic fatty liver disease by damaging the intestinal barrier.