NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Study sheds light on key steps in the HIV life cycle

Researchers were able to uncover key steps in HIV replication by reconstituting and watching these events unfold outside the cell.

Education programs may improve young children's asthma control

A combination of health programs at school and home appeared to improve asthma control in preschool children from low-income families.

Final report confirms remdesivir benefits for COVID-19

The antiviral drug remdesivir shortened recovery time for patients hospitalized with COVID-19, based on results from the completed trial.

Brain differences in youth linked to increased waist size

Cellular differences in a brain area that plays a key role in reward and food processing may predict higher obesity in children.

Machine learning detects early signs of osteoarthritis

Using artificial intelligence and MRI scans, researchers identified signs of osteoarthritis three years before diagnosis.

SARS-CoV-2 may use key carbohydrate to infect cells

A carbohydrate called heparan sulfate, which is found on cell surfaces, may play a critical role in the novel coronavirus’ ability to infect cells.

Pain rising among younger Americans with less education

Younger Americans with less than a bachelor’s degree reported higher levels of pain than today’s older adults did at their age.