NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Experimental coronavirus vaccine highly effective

Clinical trial results showed that the vaccine developed by NIH and Moderna is 94.1% effective in preventing symptomatic COVID-19.

2020 Research Highlights - Basic Research Insights

Noteworthy NIH advances in basic research include progress in understanding SARS-CoV-2, discovery of an exercise-induced protein that generates new brain cells and improves memory, and a new pain-suppression center in the brain.

2020 Research Highlights - Human Health Advances

NIH accomplishments in disease prevention, diagnosis, and treatment include COVID-19 vaccines and treatments, better diagnosis of prostate cancer, and methods for early detection of Alzheimer’s disease.

2020 Research Highlights - Promising Medical Findings

NIH findings with potential for enhancing human health include new approaches to COVID-19, a universal mosquito vaccine, and advances in restoring vision.

Financial problems can be sign of dementia onset

Older adults had problems managing financial obligations up to six years before a diagnosis of Alzheimer’s disease or related dementia.

Antibodies and T cells protect against SARS-CoV-2

Monkeys with the highest levels of antibodies against SARS-CoV-2, the virus that causes COVID-19, were best protected against reinfection. Immune cells called T cells also helped prevent reinfection.

Stress may awaken dormant cancer cells

Researchers found that stress may help awaken dormant tumor cells, causing cancer to recur. The findings suggest targets to investigate for preventing cancer relapse.