NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Memories involve replay of neural firing patterns

Researchers found that the distinct firing patterns of individual neurons that the brain uses when forming memories are replayed when remembering the experience.

Artificial intelligence predicts heart disease risk from CT scans

Artificial intelligence-based analysis of CT scans predicted people’s risk of heart disease more accurately than current methods.

Irregular sleep patterns may raise risk of heart disease

Researchers found that irregular sleep patterns—varying the timing and amount of sleep—may increase the risk of developing cardiovascular disease in people ages 45 to 84.

Bone-building protein delivered orally to mice using plants

Diabetic mice fed plants that were engineered to carry a bone-building protein showed accelerated healing of bone fractures.

New blood test method may predict Alzheimer's disease

A blood testing technique to detect Alzheimer’s disease could enable earlier treatments and testing of novel approaches.

Novel coronavirus structure reveals targets for vaccines and treatments

Researchers produced a detailed picture of the part of SARS-CoV-2—the novel coronavirus that causes COVID-19—that allows it to infect human cells.

When more information may not lead to better decisions

Researchers found that more information doesn’t always help lead those who have personal experience in a subject to make better decisions.