NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Test vaccine active against many HIV strains

An experimental HIV vaccine prompted animal immune systems to form antibodies that neutralize dozens of HIV strains. A study of the test vaccine in people is being planned.

Gut microbes affect antitumor activity in liver

A connection between bacteria in the gut and antitumor immune responses in the liver enhances our understanding of liver cancer and suggests new approaches to treat it.

Healthy diets linked to lower risk of hearing loss in women

A long-term study found that women with certain healthy dietary patterns had a lower risk of moderate to severe hearing loss.

Adaptive deep brain stimulation for Parkinson's disease

Researchers designed a self-tuning deep-brain stimulation device and tested it in two patients with Parkinson's disease.

How opioid drugs activate receptors

Researchers found that opioid drugs and the brain’s natural opioids activate nerve cell receptors differently.

MRI glove enables imaging of moving joints

A flexible glove enables MRI scans of a moving hand.

Squirrel hibernation tricks suggest medical uses

Understanding the ways that animals survive hibernation during cold weather could help researchers design better methods for storing human tissues for transplants.