NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Daily aspirin shows no benefit for healthy older adults

A large clinical trial found that a daily low-dose aspirin doesn’t have the same benefits for healthy older adults as it does for those who’ve had a heart attack or stroke.

Exercise and new nerve cell growth in Alzheimer's disease

In a mouse model of Alzheimer's disease, access to exercise stimulated the growth of new nerve cells in the brain and reduced memory problems. The findings pave the way for studies in people.

Regrowing neurons across scarred spinal tissue

Researchers stimulated neurons to regrow across scarred spinal tissue in rodents.

Fasting increases health and lifespan in male mice

Long periods of fasting between meals helped male mice live longer and healthier lives, regardless of the content of their diets.

Machine learning predicts risk of aneurysm

Researchers used machine learning to develop a method of predicting which people are at risk of developing an abdominal aneurysm.

Regenerating light-sensing eye cells in mice

Researchers restored some vision in mice with congenital blindness by changing supportive cells in the retina called Müller glia into light-sensing cells.

Device improves survival after sudden cardiac arrest

A device for supplying oxygen after sudden cardiac arrest outside of a hospital improved survival compared with a more common but invasive and difficult procedure.