NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Antibody combination suppresses HIV

In an early trial, a combination of two antibodies suppressed blood levels of HIV for months after treatment in some people.

Wearable ultrasound patch tracks blood pressure

Researchers engineered a blood pressure sensor that uses ultrasound technology and can be worn as a flexible skin patch.

Fecal transplants restore gut microbes after antibiotics

Using fecal transplants, researchers restored beneficial bacteria in cancer patients who received antibiotics for stem cell transplant procedures.

Human skeletal stem cell identified

Researchers discovered a self-renewing human skeletal stem cell. This study may one day lead to ways to restore bone, cartilage, and supportive tissues for organs.

Senescent cells linked to brain disease in mice

Eliminating old or damaged cells that have stopped dividing reduced signs of brain disease in mice—an important clue for developing treatments for neurodegenerative brain diseases.

Gut communicates directly with brain

The discovery of direct neural connections between the gut and the brain in mice could lead to a better understanding of appetite and gut health.

Most tumors in body share important mutations

Primary and metastatic tumors within an individual all likely rely on the same mutations to grow and spread, suggesting that precision treatments could be chosen based on a single sample.