NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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How night shifts disrupt metabolism

The rhythms of certain metabolic pathways can become shifted by even a few days of being awake at night and asleep during the day. Further research is needed to explore how this finding may play a role in health risks observed in people who work at n...

Early family experience affects later romantic relationships

Children who grow up in a positive family climate are better equipped to have a healthy romantic relationship as a young adult.

Editing T cell genomes without viruses

Researchers developed a way to genetically modify T cells using a jolt of electricity instead of a virus. This method may help expand the medical potential of gene editing.

Protective liquid enables oral insulin delivery in rats

Researchers developed a way to package insulin into pills that lowered blood sugar safely in rats. The approach could lead to an oral insulin option for people with diabetes.

Technique may improve detection of breast tumors

A small study found that a fast, safe, and more comfortable alternative to mammography provided enough detail for early breast tumor detection. Larger studies are being planned.

Eliminating senescent cells extends healthy life in mice

Drugs that lowered the number of non-functional (senescent) cells in the body helped mice live longer and maintain their physical abilities.

Treatment for depression in young children

Researchers found that a therapy-based approach focused on emotional development may be an effective option for treating early childhood depression.