NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Preserving sperm stem cells restores fertility in mice

Scientists stored stem cells that produce sperm for months and used them to restore fertility in male mice. The approach could potentially help young boys undergoing chemotherapy.

Immune culprits linked to inflammation and bone loss in gum disease

Researchers identified specific immune cells that, when triggered by bacteria, drive gum disease. The findings reveal potential treatment targets.

Vaccine protects animals against anthrax and plague

Scientists engineered a vaccine that protects animals from both anthrax and plague. After more development and testing, the approach could be used to combat public health threats.

Antipsychotics not helpful for delirium in ICU

A study suggests that the common practice of prescribing antipsychotic drugs to treat delirium in intensive care units may need to be reassessed.

Delayed pushing doesn't help during labor

Women who pushed earlier during labor were as likely to have a vaginal birth as those who delayed, and had fewer complications. The finding may change recommendations made to many women.

How gentle touch can turn painful after injury

Researchers identified a gene that’s needed for gentle touch to turn painful after an injury. The study uncovers a possible target for treatments to relieve pain caused by skin injuries.

Probiotic bacteria block harmful microbe

Researchers identified how Bacillus bacteria, which are used in many probiotic formulations, can prevent the growth of harmful Staphylococcus aureus, or “staph,” bacteria.