NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Ebola antibody treatment tested in people

A treatment for Ebola developed from a survivor’s protective antibody was found safe in a study of healthy volunteers at the NIH Clinical Center.

Patch replaces damaged retinal cells

Researchers developed a biodegradable patch for replacing diseased cells in the eye with healthy ones. The findings provide the basis for preliminary safety tests of the method in people.

Printed scaffolds promote spinal cord repair in rats

Researchers used 3D printing technology to create a scaffold that helped promote the growth of new nerve cells in rats and restore some limb movement after spinal cord injury.

Blood-brain barrier test may predict dementia

A new study suggests that measuring the breakdown of the blood-brain barrier could be an early way to test for cognitive impairment from Alzheimer’s disease and other causes.

School nutrition policies reduce weight gain

Implementing nutrition policies at middle schools limited unhealthy weight gains in students. The findings highlight an effective obesity prevention strategy in schools.

Genes linked to abnormal bone density and fracture

Using information from hundreds of thousands of people, researchers produced a detailed analysis of the genetic factors related to bone density.

Physical activity may reduce depression symptoms

Researchers found that sleep problems, lack of energy, and physical inactivity may lead to a depressed mood. The findings reverse conventional wisdom that depression leads to physical inactivity.