NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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3D-printed bioreactor builds bone

Bioengineers repaired jawbones in sheep using tissue grown in a 3D-printed bioreactor. The findings lay the groundwork for developing and testing the approach in people.

Drug mimics human antibody against flu

Researchers developed and tested a drug in mice that works like a human antibody to neutralize flu viruses. The study will aid development of new drugs against flu viruses.

Comparing treatments for atrial fibrillation

A study comparing a surgical procedure called catheter ablation with medications for atrial fibrillation will help inform treatment decisions.

Replacing function of impaired cystic fibrosis protein

A widely used antifungal drug replaced the function of the mutated protein that causes cystic fibrosis in human lung cells grown in the lab, suggesting a potential therapy.

Supportive parenting can reduce child's anxiety

Teaching parents ways to respond to their child's anxiety may reduce symptoms as well as the standard therapy treatment for childhood anxiety.

Blocking a pathway to heart failure

Researchers identified drugs to restore heart muscle function in rodents with heart failure. The findings may help pave the way for a similar approach in people.

Getting active later in life brings benefits

People who were inactive as teens and young adults but increased physical activity in middle age saw the same reduced risk of death as those who stayed active from adolescence onward.