NIH Research Matters

Kidney transplant recipients with two copies of a certain DNA sequence deletion had an increased risk of transplant rejection. This risk was highest when the donor had one or more copies of the intact sequence.

In a short-term clinical trial, many patients with mild persistent asthma didn’t respond any better to inhaled steroids than placebo. The study suggests a way to help guide personalized treatments.

Engineered phages were used to treat a teenager’s life-threatening antibiotic-resistant infection. The approach could be used to combat otherwise untreatable infections.

Researchers identified ways that immune cells and joint cells interact to produce the inflammation and tissue damage seen in rheumatoid arthritis.

When people ate a diet full of highly processed foods, they consumed more calories and gained more weight than when they ate a minimally processed diet.

A resource of gene expression patterns from the brain cells of people who had Alzheimer's disease may enable advances in understanding how the disease develops.

Researchers showed that levels of free fatty acids in the blood can help identify children who have eaten too close to a blood test for type 2 diabetes.