NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Bacteria enriched in marathon runners

Researchers found that marathon runners have more bacteria that metabolize lactate after finishing their race. The findings suggest strategies to enhance exercise ability.

Diagnosing COPD

A simple measurement can be used to diagnose clinically significant airflow obstruction, the key characteristic of COPD. The findings may lead to earlier detection and treatment.

Diversity enhances genomic analyses

By exploring the genomes of non-European people, researchers identified new genetic variants associated with conditions like kidney disease and diabetes.

Stress links poverty to inflammation and heart disease

In people with lower incomes, stress-related brain activity was linked to more inflammation in the body. This may explain why people with lower incomes have a higher risk of heart disease.

Gut microbe provokes release of inflammatory substance

Researchers discovered how a gut microbe linked to Crohn’s disease may stimulate immune cells to trigger inflammation.

Social acceptance helps mental health after war trauma

Researchers found that acceptance and support from community and family may lessen the toll of mental health conditions experienced by former child soldiers.

Language patterns may predict psychosis

In a proof-of-concept study, spoken language patterns predicted which people at risk for psychosis would progress to full psychosis within two years with 93% accuracy.