NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Drug may slow development of type 1 diabetes

An experimental drug called teplizumab may delay development of type 1 diabetes in people at high risk for the disease

Asthma cases dropped when air pollution declined

Drops in outdoor air pollutants over a 21-year period in Southern California were associated with 20% fewer asthma diagnoses in children.

Artificial light during sleep linked to obesity

Women who slept with a television or light on were more likely to gain weight and develop obesity. The findings suggest that turning off lights at bedtime could help keep off extra pounds.

Technique lowers risk of complications in heart valve replacement

Researchers devised a technique to avoid a fatal complication during a procedure to replace the heart’s mitral valve.

Microbiome influences risk of preterm birth

Researchers found that the vaginal microbiome changes substantially during pregnancy. Patterns of changes early in pregnancy may help identify women at high risk for preterm birth.

How many steps for better health?

Researchers found that older women who took more steps per day had a lower risk of dying until 7,500 steps a day, beyond which the benefit leveled off.

Gene deletion raises risk of kidney transplant rejection

Kidney transplant recipients with two copies of a certain DNA sequence deletion had an increased risk of transplant rejection. This risk was highest when the donor had one or more copies of the intact sequence.