NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Antibiotics prescribed more often during telemedicine visits

Researchers found that doctors treating children for respiratory infections were more likely to prescribe antibiotics during telemedicine visits than at urgent care or primary care clinics.

Drug helps people with rare chronic immune disorders

An FDA-approved drug dramatically improved the health of people with rare chronic immune disorders called hypereosinophilic syndromes.

Bioengineered vessels transform into living blood vessels

Bioengineered vessels that were implanted in people to aid with kidney dialysis matured into living blood vessels, showing that they can be integrated into human tissues.

Virus helps bacteria evade immune system

Researchers discovered how a type of virus that infects bacteria can help the bacteria escape the immune system and cause chronic wound infections.

Small molecule targets cause of adult onset muscular dystrophy

Researchers designed a small molecule that, in mice, blocks the mutated RNA responsible for adult onset muscular dystrophy. The findings suggest a new avenue to develop therapeutics.

Primate study shows progress with cryopreserved testicular tissue

A live monkey produced with sperm derived from animals that had not yet undergone puberty is an important step toward offering young cancer patients a chance to have children in the future.

Prescribing healthy foods could bring cost-effective benefits

A sophisticated model estimated that healthy food subsidies could save billions in health care costs and prevent hundreds of thousands of heart disease deaths and diabetes cases.