NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Predicting response to immunotherapy

Studies show progress in learning to predict which patients are most likely to respond to certain cancer treatments known as immune checkpoint therapies.

Learning about fatal opioid overdoses changes prescribing behavior

Notifying clinicians that one of their patients died of an opioid overdose reduced the number and doses of opioid medications prescribed in the following months.

Responsive parenting affects childhood weight

Teaching first-time mothers how to respond to their infant’s body cues reduced the child’s weight by age 3 compared with a control group.

Exploring induced labor for full-term pregnancy

A large study found that, for healthy women, inducing labor at full term rather than waiting for natural labor doesn’t increase the risk of major complications for newborns.

Impaired brain drainage in aging and Alzheimer's

Researchers gained insights into how the waste clearing vessels in the brain change as mice age. The results suggests a possible way to combat the cognitive decline seen in aging and age-related diseases.

Dairy fatty acids not linked to death in older adults

A study of older adults found that long-term exposure to dairy fats wasn’t associated with overall risk of death or death from cardiovascular disease.

How drugs could repair damage from multiple sclerosis

Drugs that help repair the nerve cell lining that’s damaged in multiple sclerosis were found to target certain enzymes. The finding could help researchers develop new treatments for multiple sclerosis.