NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Scientists define molecule's role in itch and pain pathways

Researchers defined the neural pathways for itch sensation and identified a signaling molecule called somatostatin that enhances itch and blunts pain in mice.

Brain network for social understanding develops in early childhood

A new study reveals that a network of brain areas involved in interpreting other people’s states of mind has started developing by age three.

Minoxidil may improve blood vessel structure

Minoxidil, when given orally to mice, changes blood vessel structure to reduce stiffness and increase blood flow to the brain. The drug may have potential for people with certain health problems.

Thirst circuitry mapped in the brain

Researchers mapped the wiring of the thirst center in the mouse brain, providing a glimpse into the rules that govern how brain circuits regulate fluid intake.

Smiles affect response to stress

In a study of men who were stressed by having to give short speeches, seeing different types of smiles affected the men’s stress responses differently.

Controlling childhood asthma

New study findings raise doubt about the common practice of increasing inhaled steroid dose in young children when asthma symptoms begin to worsen.

Intermittent dietary restriction may boost physical endurance

Mice fed a standard diet but deprived of food every other day developed more efficient energy metabolism and improved running endurance. The findings pave the way for studies in people.