NIH Research Matters

Mice fed a standard diet but deprived of food every other day developed more efficient energy metabolism and improved running endurance. The findings pave the way for studies in people.

A study found that people are more likely to survive a cardiac arrest if a bystander uses a defibrillator while waiting for emergency medical services to arrive.

A small molecule prevents herpes simplex-1 virus from making viral proteins. The finding suggests a new class of molecule that may be useful for developing antiviral treatments.

Patterns of gene expression in the brains of people with five major mental disorders suggest some overlapping mechanisms.

Researchers found that certain biological differences didn’t predict whether someone would lose more weight from a low-fat or low-carbohydrate diet.

Researchers found that a compound called an NAD+ precursor helped mice with features of Alzheimer's disease perform better on learning and memory tests.

Scientists found agents that, when injected into a tumor, direct the mouse immune system to destroy tumors of the same type throughout their bodies. The approach might be applied to many forms of cancer.