NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Ear tubes or antibiotics for repeat infections in children?

A study found that placing tympanostomy tubes in young children did not reduce the overall number of ear infections any more than oral antibiotic treatment.

Airway-on-a-chip screens drugs for use against COVID-19

Researchers used an airway-on-a-chip that mimics living lung tissue to screen approved drugs for use against SARS-CoV-2.

System turns imagined handwriting into text

Researchers developed a system for people with paralysis that quickly translates brain signals for handwriting into text.

Nanoparticle vaccine against various coronaviruses

A nanoparticle-based vaccine protected monkeys against SARS-CoV-2 and elicited antibodies that could neutralize a range of coronaviruses.

Delivering RNA therapies to brain tumors

A combination of nanoparticle packaging and focused ultrasound allowed an RNA therapy to be delivered across the blood-brain barrier in mice.

App may help identify children with autism spectrum disorder

Researchers developed a prototype app that screens toddlers for autism spectrum disorder by tracking eye movements during videos on a tablet or smartphone.

Supplement improves glucose metabolism in women's muscle

The muscles of women who took a supplement called nicotinamide mononucleotide for 10 weeks had improvements in the ability to process sugar.