NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Frequent testing reduced COVID-19 deaths in nursing facilities

Nursing facilities that tested their staff frequently for COVID-19 had substantially fewer deaths from the disease among their vulnerable residents.

Racial disparities in pulmonary fibrosis outcomes

Patients with pulmonary fibrosis who identified as Black were diagnosed, hospitalized, and died younger than White and Hispanic patients.

Unexpected role for the nervous system in anaphylaxis

Researchers found evidence that the nervous system plays a key role in the extreme and sometimes deadly allergic reactions known as anaphylaxis.

Woman potentially cured of HIV using transplant with cord blood stem cells

A woman with leukemia is likely cured of HIV after receiving a transplant including stem cells from banked umbilical cord blood.

Artificial pancreas controls blood sugar in young children with type 1 diabetes

Children aged 2 to 5 with type 1 diabetes who received an artificial pancreas had more stable blood glucose levels than those who received standard care.

Complete wiring map of the insect brain

The first complete wiring map of the larval fruit fly brain could aid future brain research and inspire new machine learning architectures.

Temperature-stable TB vaccine is safe and provokes immune response

An experimental tuberculosis vaccine that can be stored at room temperature was safe and provoked an immune response in a phase 1 clinical trial.