NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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New insights into the brain's motor cortex

A brain region long known to control specific muscle movements also has a more complex role related to planning and coordinating movements.

Antibiotic can help prevent common sexually transmitted infections

Taking the oral antibiotic doxycycline within three days after unprotected sex reduced the risk of sexually transmitted infections among those at increased risk.

Immune system profiles of extremely long-lived people

In a small study, researchers were able to identify distinct features of the immune systems of extremely long-lived people.

Drug may not prevent dangerously heavy bleeding after Cesarean delivery

Tranexamic acid didn’t reduce maternal deaths or the need for blood transfusions in those undergoing either scheduled or emergency Cesarean delivery.

Buprenorphine use in the emergency department safe for people who use fentanyl

Researchers found that buprenorphine can be safely started in the emergency department by people who use fentanyl either alone or with other drugs.

Relieving treatment-resistant depression in older adults

For older adults whose depression persisted while taking an antidepressant, adding aripiprazole had greater benefits than switching to another antidepressant.

Targeted protein delivery using bacterial injection system

Researchers developed a protein delivery system that can be customized to target specific human cell types.