NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Mapping how cancers form and spread

3D maps of cancer produced by an NIH initiative provide critical information on how tumors develop, spread, and respond to treatments.

Weight-loss surgery has lasting benefits in teens

Teens who had bariatric surgery to treat severe obesity had sustained weight loss a decade later and fewer obesity-related health problems.

Early-life sugar intake affects chronic disease risk

Low sugar exposure in utero and in the first two years of life was associated with lower risks of diabetes and high blood pressure.

Assessing ways to gauge aging status

Researchers found that grip strength, knee strength, and balance—especially the ability to stand on just one leg—decline significantly in the decades after age 50.

Study of H5N1 from an infected person

An H5N1 flu virus isolated from an infected farm worker could transmit through airborne droplets and was lethal in mice and ferrets.

Implantable device reverses opioid overdose in animals

An implantable device detected opioid overdose and automatically administered naloxone, saving lives in rat and pig models.

Atlas of Alzheimer's disease progression

An atlas of cellular changes in the brain during Alzheimer's disease revealed two distinct phases of disease progression.