NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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2024 NIH Research Highlights - Promising Medical Findings

NIH findings with potential for enhancing human health include insights into the mechanisms of ME/CFS, a skin test to detect Parkinson's disease and related disorders, and a promising target for cataract drug development.

Chromosome abnormalities found in healthy breast tissue

Researchers found that normal human breast tissue harbors rare cells with chromosome abnormalities previously linked to invasive cancers.

Potential new target for treatment of inflammatory bowel disease

In mice with a condition similar to inflammatory bowel disease, blocking a cellular process called SUMOylation stopped inflammation and tissue damage.

Wildfire smoke exposure and dementia risk

Wildfire smoke exposure was associated with greater odds of being diagnosed with dementia.

Liver-brain communication affects eating patterns and obesity

Disrupting the liver’s circadian clock genetically or with a high-fat diet altered eating patterns in mice.

How sleep leads to healing after heart attack

Scientists found that after heart injury, immune cells called monocytes travel to the brain and trigger a deep sleep that promotes recovery in both mice and people.

Characterizing what human sensory nerves can sense

Researchers analyzed gene activity in different human sensory nerve cells to predict which would respond to stimuli such as heat, cold, and pressure