NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Tiny tardigrades may hold clues to cancer care

Researchers found that a protein made by tiny creatures called tardigrades can protect mouse and human cells from radiation damage.

Non-opioid compound for chronic pain relief

Scientists developed a compound that appeared to relieve pain in mice without adverse side effects.

Neutralizing noroviruses

Researchers found evidence that the human immune system can produce antibodies to neutralize diverse norovirus strains and types.

Improving gene editing in the liver

Researchers designed a gene-editing system that replaced up to a quarter of the main type of cell in the mouse liver with edited cells.

Predicting preeclampsia

Researchers developed an approach that can predict preeclampsia in pregnant women as early as the first trimester by using cell-free DNA in blood samples.

Mapping MS-like lesions in marmosets

Researchers constructed a map of molecular and cellular changes in marmoset brains that occur in developing lesions like those in multiple sclerosis (MS).

Tracking diet from stool samples

Researchers developed a way to track what people ate by analyzing DNA from stool samples.