NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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How exercise can protect against Alzheimer’s

Mouse studies give insights into how exercise might help protect against Alzheimer’s disease.

Education levels may affect mortality trends

Mortality rates in 2023 were higher than expected based on earlier trends, especially among those who did not graduate from college.

Home test kits boost screening for cervical cancer

Women who used at-home test kits were more than twice as likely to complete screening for cervical cancer than women who received only telephone reminders. 

Slowing malaria by treating mosquitoes

Researchers identified compounds that could kill malaria parasites inside mosquitoes.

Cysteine restriction plays key role in weight loss

Studies in people and mice show a diet that’s low in the amino acid cysteine reprograms fat to burn more calories, triggering weight loss and reduced inflammation.

Y chromosome loss plays complex role in cancers

Loss of the Y chromosome in both tumor and immune cells may hamper immune protections and lead to poorer outcomes for men with different types of cancer.

Millions of U.S. kids live with parents with substance use disorders

Almost 19 million U.S. children—1 in 4—lived with at least one parent or primary caregiver who had a substance use disorder in 2023.