NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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A cellular map of brain lesions in multiple sclerosis

Researchers created a detailed map of cells in the expanding lesions involved in more disabling forms of multiple sclerosis.

Opioid overdose deaths rise among Black Americans

While opioid overdose deaths remained flat overall between 2018 and 2019, they rose sharply for Black Americans.

Drugs treat spinal disc degeneration in mice

Scientists reduced age-related disc degeneration in mice using an experimental drug combination that targets aging cells.

Genomic origins of lung cancer in never smokers

Researchers identified three subtypes of lung cancers in people who never smoked. The results could help guide more precise lung cancer treatments.

Parents' smoking during childhood linked to rheumatoid arthritis later in life

A study found that girls whose parents smoked cigarettes were 75% more likely to develop rheumatoid arthritis as adults.

Misdirected antibodies linked to severe COVID-19

Antibodies that mistakenly target the body’s own immune-system proteins may account for about 20% of COVID-19 deaths.

Hormone links exercise with cognitive benefits

Researchers found that irisin, an exercise-induced hormone, improves cognitive performance in mice.