NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Understanding SARS-CoV-2 antibody binding

Researchers mapped where various antibodies bind to the SARS-CoV-2 spike protein. The results could lead to more effective COVID-19 therapies.

Repeats in the genetic code underlie some human variation

Researchers found that differences in repeats of DNA explain substantial variations in height, kidney function, hair curl, and blood lipids.

Test may help reduce racial disparities in kidney disease

Researchers found that measuring levels of a protein called cystatin C can accurately estimate kidney function without needing to take race into account.

Trends in U.S. methamphetamine use and associated deaths

Researchers found that risky patterns of methamphetamine use and the diversity of people who used methamphetamine increased between 2015 and 2019.

Moderna COVID-19 vaccine generates long-lasting immune memory

People who received low doses of the Moderna COVID-19 vaccine had strong immune memories of the virus six months after being fully vaccinated.

Critical time window for rehabilitation after a stroke

Researchers found that intensive therapy, added to standard rehabilitation, produces the greatest improvement when administered 2-3 months after a stroke.

A cellular map of brain lesions in multiple sclerosis

Researchers created a detailed map of cells in the expanding lesions involved in more disabling forms of multiple sclerosis.