NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Cancer cells drain energy from immune cells

Researchers found that cancer cells use straw-like nanotubes to siphon mitochondria from immune cells, essentially draining their energy.

Brain receptor linked to puberty and growth

Researchers identified a brain receptor that links childhood nutrition to the timing of puberty and growth.

Scientists identify a culprit for chronic itch

The discovery of an immune substance that sensitizes and enhances the activity of itch-sensing neurons suggests a treatment strategy for persistent itchy skin conditions.

Searching for new antibiotics in the human body

Researchers identified tiny pieces of protein produced by the body that could be synthesized and potentially developed into new antibiotics.

Repurposing drugs to treat age-related macular degeneration

Researchers found that the antidepressant fluoxetine blocks the inflammation that leads to dry age-related macular degeneration, or AMD, a common cause of vision loss.

SARS-CoV-2 infection of the inner ear

Researchers found that SARS-CoV-2 can infect inner ear cells, which could explain the hearing and balance issues in some COVID-19 patients.

Therapy has long-lasting benefits for children with cerebral palsy

Sixty hours of a therapy called CIMT led to significant improvements in hand and arm function among children with cerebral palsy in a randomized trial.