NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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COVID-19 immune response improves for months after vaccination

Researchers showed that B cells evolve after COVID-19 vaccination to help improve protection against SARS-CoV-2 over time.

Getting sufficient sleep reduces calorie intake

In a randomized clinical trial, overweight adults who increased how much they slept took in fewer calories.

Use of melatonin supplements rising among adults

The use of melatonin supplements by adults in the United States more than quintupled between 1999 and 2018.

Calorie restriction, immune function, and health span

A study of moderate calorie restriction in people led to the identification of a gene that is involved in improved immune and metabolic functions.

Compound produced by bacteria protects the skin

Researchers discovered how a bacterium that lives on the skin, called S. epidermidis, helps protect the skin from water loss and damage.

COVID-19 vaccines induce immune response to Omicron

Studies found that COVID-19 vaccines elicit T cells that recognize the Omicron variant despite the many mutations in its spike protein.

Identifying immune cells for personalized cancer immunotherapy

A new technique identified rare immune cells found in patients’ tumors that can recognize and potentially kill cancer cells.