NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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E-cigarettes may complicate teen attempts to quit nicotine

Among U.S. teens, unsuccessful attempts to quit smoking rose in 2020 after years of decline—a reversal that might relate to the recent rise in vaping.

Understanding how the brain tracks social status and competition

In mouse studies, researchers gained insight into how different brain areas help process information related to social status, competition, and other group dynamics.

First complete sequence of a human genome

Researchers finished sequencing the roughly 3 billion bases (or “letters”) of DNA that make up a human genome.

Nasal antiviral blocks SARS-CoV-2 infection in mice

A compound delivered into the nose blocked a protein used by SARS-CoV-2 to get into cells and prevented severe infection in mice.

Antibodies recognize new SARS-CoV-2 Omicron variant after booster

After a booster vaccination, levels of antibodies in the blood that could bind to and neutralize a new Omicron subvariant increased substantially.

Compound blocks excess mucus secretion in mouse lungs

In mice, a compound called SP9 blocked the excess secretion of mucus, a feature of many lung diseases that can cause difficulty breathing and other symptoms.

System reveals 3D details of living tissues

Researchers developed a system that allows for real-time 3D imaging of living tissues without the need for any dyes.