NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Compounds block pain without sedation in mice

Researchers identified several compounds that activate a specific pain-blunting receptor on cells.

Bionic pancreas simplifies management of type 1 diabetes

A bionic pancreas managed blood glucose levels in people with type 1 diabetes better and with less user input than existing methods.

Popular diabetes drugs compared in large trial

A comparison of four common drugs for treating type 2 diabetes showed that two outperformed the others in maintaining target blood sugar levels.

How diet may disrupt gut microbes to promote weight gain

Mice fed a high-sugar diet lost immune cells in their guts that normally help regulate the absorption of dietary fat.

Daily multivitamin may improve cognition in older adults

In a clinical trial, cocoa extract did not improve cognitive function in older adults, but a daily multivitamin did.

Telehealth improves treatment for opioid use disorder

People with opioid use disorder who received telehealth services were more likely to stay on their medications and had a lower risk of overdose during the COVID-19 pandemic.

Swarm of tiny robots scrub teeth

Tiny magnetically controlled “robots” that can scrub experimental teeth might one day be adapted to help people who lack the fine motor skills to brush and floss on their own.