NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Experimental cat allergy shots provide longer-lasting relief

An experimental approach that combines cat allergy shots with a monoclonal antibody led to more effective relief that continued a year after treatment ended.

How timing of eating affects metabolism and weight gain

A study in mice found that eating burns more energy when restricted to certain times of the day.

Skin compounds associated with attractiveness to mosquitoes

People with higher levels of compounds called carboxylic acids on their skin were more attractive to mosquitoes, and remained so for years.

"Slow" vaccine delivery improves immune response to HIV

An experimental HIV vaccine, delivered as increasing doses over several days, led to long-lasting and diverse antibody production in monkeys.

Potential contributor to sex differences in Alzheimer's risk

An enzyme that is more abundant in women contributes to the buildup of tau tangles in the brain, a hallmark of Alzheimer's disease.

Robotic exoskeleton helps people walk

Researchers created a robotic leg exoskeleton that provides personalized walking assistance under real-world conditions.

Compounds block pain without sedation in mice

Researchers identified several compounds that activate a specific pain-blunting receptor on cells.