NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Biomarker tracks recovery from depression

Researchers identified a unique pattern of brain activity, a “biomarker,” that can detect a patient’s response to deep-brain stimulation for treating severe depression.

Immune response to eating chitin linked to better health

Eating a type of dietary fiber called chitin evoked an immune response in mice that was linked to better metabolic health.

Touch-sensing protein plays role in sexual response

A protein called PIEZO2, which helps the body to sense light touch, appears to be involved in normal genital sensitivity.

Tiny implanted devices give insights for treating brain tumors

A tiny device implanted during brain surgery could help provide personalized information about a tumor’s potential responses to cancer-fighting drugs.

Cold virus may set the stage for Long COVID

Prior infection with a common cold coronavirus may predispose some people to develop Long COVID.

A potential blood test for Parkinson's disease

A blood test that measures damage to cells' mitochondria was able to distinguish people with Parkinson's disease from those without.

Advancing molecular insights into cancer

A resource built with genomic, proteomic, and clinical data from more than 1,000 tumors across 10 cancer types can help researchers uncover new molecular insights into how cancers develop and progress.