NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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PET scans of heart may aid early detection of Lewy body diseases

PET scans of the heart may help to identify which at-risk people will later develop Parkinson’s disease or dementia with Lewy bodies.

Intermittent fasting for weight loss in people with type 2 diabetes

People with obesity and type 2 diabetes lost more weight using daily periods of fasting than by trying to restrict calories over a six-month period.

Cardiovascular deaths likely to rise from extreme heat

Researchers estimated there will be an increase in cardiovascular deaths due to extreme heat between now and mid-century.

Liquid biopsies and AI give insight into eye health and aging

Researchers developed a technique to assess thousands of proteins in eye fluids and identify cellular drivers for disease and aging.

Scientists build largest maps to date of cells in human brain

International research teams created highly detailed cellular maps of adult and developing human brains, along with the brains of other animals.

Calorie restriction and human muscle function

Calorie restriction resulted in changes in human muscle cells consistent with improved muscle health.

Immune boost may protect against multiple hospital-acquired infections

A novel type of vaccine designed to stimulate the innate immune system provided protection for mice against a wide range of bacteria and fungi.