NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Anti-diabetes drugs may reduce the risk of colorectal cancer

People with diabetes who took drugs called GLP-1 receptor agonists had a lower risk of colorectal cancer compared with those prescribed other diabetes drugs.

Tracking organ aging and disease

Researchers found that proteins in the blood can be used to track the aging of individual organs, and that faster organ aging increased the risk of disease and death.

Cochlear nerve damage associated with tinnitus

People with chronic tinnitus were more likely to have signs of damage to their cochlear nerve than people without the condition.

2023 NIH Research Highlights - Promising Medical Findings

NIH findings with potential for enhancing human health include insights into Long COVID and ME/CFS, and a promising blood test for early Alzheimer’s detection.

2023 NIH Research Highlights - Basic Research Insights

Noteworthy NIH advances in basic research include detailed cellular maps of human and nonhuman animal brains, a contraceptive that disables sperm, and a vaccine that could provide broad protection against microbes.

2023 NIH Research Highlights - Human Health Advances

NIH accomplishments in disease prevention, diagnosis, and treatment include an antibiotic to prevent sexually transmitted infections, an mRNA vaccine to treat pancreatic cancer, and an app for autism screening.

Nanoplastics may help set the stage for Parkinson's risk

Scientists found that tiny plastic particles can enter nerve cells, impair breakdown of structures linked to Parkinson's disease, and harm certain brain regions in mice.