NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
News

Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Discrimination may lead to unhealthy gut-brain changes

People who reported high levels of discrimination in their daily lives had increased brain activity in response to unhealthy food triggers.

App aids early screening for autism

A tablet-based app that records toddlers’ responses to videos holds promise for improved early detection and intervention.

How SARS-CoV-2 contributes to heart attacks and strokes

The virus that causes COVID-19 can infect coronary arteries and increase inflammation in atherosclerotic plaques.
Research in Context

Obesity and metabolic health

Losing weight and reversing obesity might seem straightforward: eat fewer calories than you burn. But that’s not as easy as it sounds. This special feature explores the many factors that affect the body’s metabolism.

Dysfunctional exosomes involved in chronic inflammation in diabetic wounds

Tiny signaling particles called exosomes isolated from the chronic wounds of people with diabetes were dysfunctional and promoted inflammation.

Immune and hormonal features of Long COVID

Immune and hormonal differences between people with Long COVID and those without shed light on possible causes of Long COVID.

Scientists find common brain network for substance use disorders

Researchers identified a common brain network that’s linked to addiction across multiple substances.