NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Adrenal cell affects parental behavior in mice

Researchers traced differences in parental care between two mouse species to a new cell type in the adrenal glands.

Unseen details of human brain structure revealed

A detailed map of all the cells and connections in a single cubic millimeter of the human brain revealed previously unseen aspects of brain structure.

Study suggests approach for treating rare disorder

Researchers used 3D brain tissue structures called organoids to test a potential therapy for a rare disorder called Timothy syndrome.

Cognitive impairment among older American Indians

The prevalence of cognitive impairment among older American Indians may be higher than previously thought, according to a new analysis.

Study defines major genetic form of Alzheimer's disease

In a study of people primarily of European descent, those with two copies of a certain gene, APOE4, predictably began to develop the underlying abnormalities of Alzheimer's disease as early as age 55.

Understanding how exercise affects the body

A study of endurance training in rats found molecular changes throughout the body that could help explain the beneficial effects of exercise on health.

Anger may harm heart and blood vessel health

Researchers found that brief bouts of anger can impair the ability of blood vessels to expand and contract, which might have consequences for heart health.