NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
News

Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Study shows how aura may lead to migraine headache

Researchers found that aura altered brain fluid in mice, which flowed directly into part of the peripheral nervous system that detects migraine pain.

Genome editing restores hearing in mice

A genome editing method restored hearing in adult mice with a rare type of genetic hearing loss and might one day help to reverse some types of hearing loss in people.

Testing transmission and infection of H5N1 from cows

Researchers found that an H5N1 flu virus from cows could infect mice and ferrets, but airborne transmission wasn’t very efficient.

Gene variant slows form of inherited Alzheimer’s disease

In a family with an inherited form of Alzheimer’s disease, those who carried a gene variant called APOE3Ch had a delay in cognitive impairment and dementia. More research is needed to see whether APOE3Ch has a protective effect in people beyond this ...

Developing treatments for prion diseases

Researchers developed a novel method to turn off prion protein production in mice. The technique could lead to treatments for prion diseases such as mad cow disease.
Research in Context

Movement after paralysis

This feature explores experimental approaches to allow people living with paralysis to become more independent and improve quality of life.

Quick test could help reduce dementia care disparities

A five-minute, culturally neutral test for cognitive problems improved dementia detection and management in older adults.