NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
News

Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
News

tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
News

Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Illustration of orange, red, and tan microbes in the gut.

Microbiome transplants may curb food allergies

Gut microbe transplants treated some peanut allergies in an early-stage clinical trial.
Doctor shows patient a diagram of the female reproductive tract.

Endometriosis may increase type 2 diabetes risk

Researchers found that some women with endometriosis may have increased risk of developing type 2 diabetes.
A disintegrating cell structure lined with tau proteins that become hyperphosphorylated and form tangles.

Scientists identify new role for tau protein in brain diseases

A study suggests that abnormal tau proteins involved in certain neurodegenerative diseases interact with mitochondria to drive a process called reverse electron transport.
Young child smiles, pointing to her teeth, during dental checkup.

Coating stops tooth decay in children

A clinical trial found that a topical treatment called silver diamine fluoride stops cavities in young children from getting worse.
Woman exercises at an outdoor gym.

Dementia-free years may decrease with smoking, hypertension, and diabetes

Researchers found that smoking, high blood pressure, and diabetes in midlife lower the number of years a person is likely to live without dementia.
Multi-colored illustration of DNA in the nucleus of a cell.

DNA organization changes in Alzheimer’s disease, aging

The 3D organization of DNA in cells changes in Alzheimer’s disease and aging, according to new research.

Childhood screen detects mental health risks

Screening for home and family stresses may help identify children at risk for depression and sleep disorders that traditional adversity screening misses.