NIH Research Matters

Middle-aged woman holds the back of her left hand to her forehead.
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Antiviral drug did not improve Long COVID symptoms

A clinical trial for Long COVID found that treating patients with a common antiviral drug for up to 25 days did not improve symptoms.
X-ray of the human lung.
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tRNA treatment may help restore cystic fibrosis proteins

Lipid nanoparticles delivering engineered transfer RNA restored functional proteins in cell and animal models of cystic fibrosis.
Medical illustration of Clostridioides difficile bacteria
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Bacterial infection may alter developing gut

C. difficile bacteria caused lasting changes to cells in the intestines of newborn mice.

 

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Severe CTE clearly linked to dementia

Researchers found a strong link between severe chronic traumatic encephalopathy (CTE) and symptoms of dementia and cognitive function.

Understanding obesity-induced inflammation

NIH-funded researchers detailed a chain of events through which obesity promotes harmful inflammation.

Sensory nerves play role in bone fracture healing

A study in mice found that after a bone fracture, the nerves that sense pain also promote healing by signaling for bone repair and wound healing.

People with dementia prescribed risky drugs

Researchers found that many older adults with dementia or cognitive impairment were prescribed medications that can increase the risk of confusion, falls, and hospitalization.

Cellular mitochondria transfer prevents pain

A new understanding of mitochondria may lead to improved treatments for nerve pain.

Testing risk-based breast cancer screening

A large clinical trial found that a personalized approach to breast cancer screening is a safe alternative to routine annual mammograms and may have other benefits.

ADHD medications stimulate alertness, motivation

Researchers found that prescription stimulants for ADHD act on brain networks that control wakefulness and reward, but not attention as previously thought.