The Division of Genomic Medicine (DGM) promotes the institute's efforts to advance the application of genomics to medical science and clinical care.
Overview
The division plans, directs and facilitates multi-disciplinary research to identify genetic contributions to human health and to advance approaches for the use of genomic data to improve diagnosis, treatment and prevention of disease; through research grants, research training grants, and contracts. The division also:
- Determines program priorities in genomic medicine and related areas and recommends funding levels.
- Assesses needs for research and research training in genomic medicine and related areas.
- Prepares reports and analyses to assist Institute staff and advisory groups in carrying out their responsibilities.
- Collaborates with the other NHGRI extramural research divisions to establish a balance of resources, personnel, and research and training budgets to achieve NHGRI goals.
- Provides expert advice to the director of NHGRI on various aspects of genomic medicine.
- Collaborates with the other NHGRI divisions, other National Institutes of Health Institutes and Centers (ICs), and other agencies and entities, national and internationally and maintains an awareness of research efforts in relevant program areas.
Research Programs and Projects
Many DGM programs and projects have working groups with similar research topics and missions.
Completed Programs
Clinical Sequencing Evidence-Generating Research (CSER)
Genetic Association Information Network (GAIN)
Genes and Environment Initiative (GEI)
Genomics and Randomized Trials Network (GARNET)
Gene Environment Association Studies (GENEVA)
Implementing Genomics in Practice (IGNITE)
Newborn Sequencing in Genomic Medicine and Public Health (NSIGHT)
The Cancer Genome Atlas (TCGA)
Training Programs Research Training
Genomic Medicine Meetings
Genomic Medicine XVI: Host Genomics and Infectious Disease
December 12-13, 2024
Genomic Medicine XV: Genomics and Population Screening
November 8-9, 2023
Genomic Medicine XIV: Genomic Learning Healthcare Systems
August 31 - September 1, 2022, Virtual
Genomic Medicine XIII: Developing a Clinical Genomic Informatics Research Agenda
February 9-10, 2021, Virtual
Genomic Medicine XII: Genomics and Risk Prediction
May 6-7, 2019, Silver Spring, Md.
Genomic Medicine XI: Research Directions in Genomic Medicine Implementation
September 5-6, 2018, La Jolla, California
Genomic Medicine X: Research Directions in Pharmacogenomics Implementation
May 2-3, 2017, Silver Spring, Md.
Genomic Medicine IX: Bedside to Bench - Mind the Gaps
April 19-20, 2016, Silver Spring, Md.
Genomic Medicine VIII: NHGRI's Genomic Medicine Portfolio
June 8-9, 2015, Rockville, Md.
Genomic Medicine VII: Genomic Clinical Decision Support - Developing Solutions for Clinical Implementation
October 2-3, 2014, North Bethesda, Md.
Genomic Medicine VI: Global Leaders in Genomic Medicine
January 8-9, 2014, Washington, D.C.
Genomic Medicine V: Working with Federal Stakeholders
May 28-29, 2013, Bethesda, Md.
Genomic Medicine IV: Physician Education in Genomics
January 28-29, 2013, Dallas, Texas.
Genomic Medicine III: Working with Implementation Stakeholders
May 3-4, 2012, Chicago, Ill.
Genomic Medicine II
Dec. 5-6, 2011, Bethesda, Md.
Genomic Medicine Symposium
June 29, 2011, Chicago, Ill.
Other Meetings and Workshops
Defining a Clinical Data Ecosystem for Genomic Health
April 10-11, 2024
NHGRI Genomic Consultation Research Working Group
February 16, 2023
Pre-Applicant Webinar for Multi-Omics for Health and Disease Consortium
September 26, 2022
Multi-omics in Health and Disease: Current Applications, Challenges and Future Directions
June 17-18, 2021
Webinar for Investigator-Initiated Research on Genetic Counseling Processes and Practices RFAs
September 25, 2020
NHGRI and NICHD dGTEx Applicant Webinar
August 3, 2020
PRS Diversity Consortium Webinar
May 15, 2020
NSIGHT Final Public Session
June 24, 2019, Bethesda, Md.
Genomics in Health and Wellness Meeting
March 5-6, 2019, Bethesda, Md.
Revisiting the Missing Heritability of Complex Diseases, Ten Years On
May 1-2, 2018, Silver Spring, Md.
Genomic Medicine for Reproductive, Prenatal and Neonatal Health
April 16-17, 2018, Bethesda, Md.
eMERGE & CSER: The Convergence of Genomics and Medicine
February 2, 2017, Bethesda, Md.
IGNITE and Beyond: The Future of Genomic Medicine Implementation
August 30, 2016, Bethesda, Md.
NHGRI International Genomics Education Meeting
August 4-5, 2016, Bethesda, Md.
Future Directions for the eMERGE Network
January 22, 2014
Research Directions in Genetically-Mediated Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
March 3-4, 2015, Bethesda, Md.
Implicating Sequence Variants in Human Disease
September 12-13, 2012, Bethesda, Md.
Sequencing in Cohort Studies and Large Sample Collections
June 28-29, 2012, Bethesda, Md.
Characterizing and Displaying Genetic Variants for Clinical Action Workshop
Dec. 1-2, 2011, Gaithersburg, Md.
Gene-Environment Interplay in Common Complex Diseases: Forging an Integrative Model
January 25, 2010, Bethesda, Md.
New Models for Large Prospective Studies Symposium
January 22, 2010, Bethesda, Md.
The Dark Matter of Genomic Associations with Complex Diseases: Explaining the Unexplained Heritability from Genome-Wide Association Studies
February 2-3, 2009, Bethesda, Md.
Epidemiology for Researchers Performing Genetic/Genomic Studies
July 18, 2008, Bethesda, Md.
Genetics for Epidemiologists: Application of Human Genomics to Population Sciences
May 13-14, 2008, Chicago, Ill.
Frontiers in Population Genomics Research Meeting
December 18-19, 2007 in Bethesda, Md.
Designing Geneticists: Study Design Issues in Population-Based Genetics and Genomics Research
October 23-27, 2007, San Diego, California
Genome-Wide Association Studies for the Rest of Us: Adding Genome-Wide Association to Population Studies
June 22, 2007, Boston, Mass.
Multi-IC Symposia on the Application of Genomic Technologies to Population-Based Studies: Facilitating Collaboration in Genome-Wide Association Studies
May 22-23, 2007, Bethesda, Md.
June 5-6, 2006, Bethesda, Md.
Funding Opportunities
NOT-HG-24-016 Notice of Special Interest (NOSI): Advancing Genomic Medicine Research through Small Businesses
NOT-HG-24-040 Notice of Special Interest: Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS)
NOT-HG-24-041 Notice of Special Interest: Small Business Solutions to Enable Regional Genomic Medicine eConsult Services
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
PAR-24-144 :
Application Receipt Date(s): May 29, 2024; September 27, 2024; May 28, 2025; September 29, 2025; May 27, 2026; September 28, 2026
Expiration Date: January 08, 2027
NOT-HG-20-035 Notice of NHGRI Interest in Receiving Letters Requesting Permission to Submit Applications to Support the NHGRI Research Training and Career Development Annual Meeting (U13)
NOT-HG-24-020 Notice of New NIH-Designated Data Repository: NHGRIs Genomic Data Science Analysis, Visualization, and Informatics Lab-space (AnVIL)
Release Date: February 29, 2024
PAR-25-144 Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
Expiration Date: January 8, 2028
PAR-25-143 Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
Expiration Date: January 8, 2028
PAR-25-233 Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
Expiration Date: January 8, 2028
PA-23-262 Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
Posted Date: September 7, 2023
PA-23-272 Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
Posted Date: August 17, 2023
PA-23-271 Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31)
Posted Date: September 12, 2023
PA-24-181 Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Clinical Trial Required)
Open Date: May 10, 2024
PA-24-182 Mentored Clinical Scientist Research Career Development Award (Parent K08 - Independent Clinical Trial Not Allowed)
Open Date: May 10, 2024
NOT-HG-22-011 Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients Use of Genomic Information
Expired Funding Opportunities
2025
Advancing Genomic Medicine Research (Clinical Trial Optional) (R01)
RFA-HG-25-002
Due Date: February 11, 2025
Expiration Date: February 12, 2025
Advancing Genomic Medicine Research (Clinical Trial Optional) (R21)
RFA-HG-25-003
Due Date: February 11, 2025
Expiration Date: February 12, 2025
Advancing Genomic Medicine Research (Clinical Trial Not Allowed) (R03)
RFA-HG-25-004
Due Date: February 11, 2025
Expiration Date: February 12, 2025
2024
Population Genomic Screening in Primary Care Cooperative Agreement (U01 - Clinical Trial Required)
RFA-HG-24-021 :
Application Receipt Date: December 02, 2024
Expiration Date: December 03, 2024
Population Genomic Screening in Primary Care Cooperative Agreement (U01 - Clinical Trials Optional)
RFA-HG-24-022
Application Receipt Date: December 02, 2024
Expiration Date: December 03, 2024
Population Genomic Screening in Primary Care Sequencing Center (U01 - Clinical Trial Optional)
RFA-HG-24-023
Application Receipt Date: December 02, 2024
Expiration Date: December 03, 2024
PAR-24-263 SBIR Solutions to Enable Population Genomic Screening (R43/R44 Clinical Trial Optional)
Application Receipt Date: December 02, 2024
Expiration Date: December 03, 2024
PAR-24-262 STTR Solutions to Enable Population Genomic Screening (R41/R42 Clinical Trial Optional)
Application Receipt Date: December 02, 2024
Expiration Date: December 03, 2024
Research on the Impact of and Methods for Implementing Regional Genomic Medicine eConsult Services (U01 Clinical Trials Optional)
RFA-HG-24-001
Application Receipt Date: May 30, 2024
Expiration Date: May 31, 2024
PAR-24-106 Solutions to Enable Regional Genomic Medicine eConsult Services (R43/R44 Clinical Trial Optional)
Application Receipt Date: May 30, 2024
Expiration Date: May 31, 2024
PAR-24-107 Solutions to Enable Regional Genomic Medicine eConsult Services (R41/R42 Clinical Trial Optional)
Application Receipt Date: May 30, 2024
Expiration Date: May 31, 2024
PAR-21-312 Genomic Curriculum Development for Medical Students (R25 Clinical Trial Not Allowed)
Application Receipt Dates: January 25, 2022; January 25, 2023; January 25, 2024
Expiration Date: January 26, 2024
2023
PAR-21-074 Mentored Research Experiences for Genetic Counselors (R25)
Application Receipt Date(s): May 25, 2021, May 25, 2022, and May 25, 2023
Network of Genomics-Enabled Learning Health Systems (gLHS) Clinical Sites (U01 Clinical Trial Required)
RFA-HG-23-041
Due Date: November 7, 2023
Expiration Date: November 8, 2023
Network of Genomics-Enabled Learning Health Systems (gLHS) Coordinating Center (U01 Clinical Trials Required)
RFA-HG-23-042
Due Date: November 7, 2023
Expiration Date: November 8, 2023
2022
The NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space Clinical Resource (ACR) (U24 Clinical Trial Not Allowed)
RFA-HG-22-021
Multi-Omics for Health and Disease - Data Analysis and Coordination Center (U01 Clinical Trial Not Allowed)
RFA-HG-22-010
Multi-Omics for Health and Disease - 'Omics Production Centers (U01 Clinical Trial Not Allowed)
RFA-HG-22-009
Multi-Omics for Health and Disease - Disease Study Sites (U01 Clinical Trial Optional)
RFA-HG-22-008
Older Archived DGM Funding Opportunities
Division Staff Leadership Program Staff Program Directors related-resources Related Resources Research Funding Genome-Wide Association Studies