An official website of the United States government
Focus on Disorders
Alzheimer's Disease and Alzheimer's-Related Dementias
NINDS-led programs that advance Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD) research, as part of the National Plan to Address Alzheimer's Disease.
Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) related information, research highlights, and resources
Epilepsy Research
Epilepsy-related information, research highlights, and resources
Parkinson's Disease Research
Parkinson’s disease-related information, research highlights, and resources
Spinal Cord Injury Research
Spinal cord injury neuroscience research-related information and resources
Traumatic Brain Injury Research
Traumatic brain injury-related information, research highlights, and resources
Undiagnosed Diseases Network
The Undiagnosed Diseases Network (UDN) is an NIH-supported research program that brings together clinical and research experts from across the United States to help diagnose and understand previously undiagnosed diseases.
Focus on Tools & Topics
Biomarkers
The NINDS biomarker program is focused on improving the quality and efficiency of neurotherapeutic clinical research toward Phase II and beyond by supporting rigorous biomarker validation.
Health Disparities
The NINDS supports a wide variety of health disparities-related programs. Learn more about what these grantees are doing across the Nation.
Neural Engineering
Neural engineering spans early concept generation, technology development/optimization, translational studies and clinical trials.
Neuroethics
The NINDS neuroethics program supports neuroethics-related research, proactively addresses ethical questions that arise from NINDS research, and provides neuroethics resources.
Stem Cell
Stem cell research-related information, research highlights, and resources in this rapidly-developing area of research.
Neural Exposome
The neural exposome is the integrated compilation of all physical, chemical, biological, and (psycho)social influences that affect nervous system health and disease.
Research Funded by NINDS
Basic Neuroscience
NINDS-supported research aimed at understanding the structure and function of the nervous system.
Clinical Research
NINDS Division of Clinical Research exists to provide support for all NINDS extramurally-funded clinical studies and trials.
Translational Research
NINDS Office of Translational Research mission is to accelerate the preclinical discovery and development of new therapeutic interventions for neurological disorders.
Research at NINDS
Labs at NINDS
Today investigators in the NINDS intramural program conduct research in the basic, translational, and clinical neurosciences at the NINDS Bethesda, Maryland, laboratories. Interests cover a broad range of neuroscience research including molecular biophysics, synapses and circuits, neuronal development, integrative neuroscience, brain imaging, neurological disorders, and stroke.
Neuroscience at NIH
The NIH is home to one of the largest neuroscience research centers in the world. Over 150 laboratories, originating from eleven different Institutes, conduct research in the basic, translational, and clinical neurosciences.
Intramural Research Programs at NIH
The Intramural Research Program (IRP) is the internal research program of the National Institutes of Health (NIH), known for its synergistic approach to biomedical science.
Blue Ribbon Panel Review
External review of the scientific achievement and overall program organization on the research conducted by NINDS in their intramural research program
Scientific Resources
Animal Models
Resources available to neuroscience researchers interested in utilizing animals as models for nervous system function.
Cell / Tissue / DNA
Various neuroscience reagents and resources can be obtained by researchers, including human DNA, biomarkers, brain bank tissue, and stem cell lines
Gene Expression
Resources available for gene expression-related information relevant to neuroscience research.
NINDS Common Data Elements
Resources available for NINDS CDEs for Investigators to utilize for research planning and implementation.
Trans-Agency Activities
Blueprint
The NIH Blueprint for Neuroscience Research is a cooperative effort among the 15 NIH Institutes, Centers and Offices that support neuroscience research to identify cross-cutting areas of research and confront challenges too large for any single Institute or Center.
CounterACT
Trans-NIH translational research program supporting basic, translational, and clinical research aimed at the discovery or identification of better therapeutic medical countermeasures and/or diagnostic technologies against chemical threat agents.
ICARE
As the primary NIH Institute for epilepsy research, NINDS leads the Interagency Collaborative to Advance Research in Epilepsy working group, with broad representation from the NIH, other Federal agencies, and the research and patient advocacy communities.
Interagency Research Coordinating Committees
Federal advisory committees created by the Department of Health and Human Services to enhance research efforts and promote collaboration across the government.
The National Plan to End Parkinson’s
The National Plan to End Parkinson’s was established in 2024 to prevent, diagnose, treat, and ultimately cure Parkinson’s and related disorders. NINDS will co-lead the Advisory Council, helping guide the plan and bring together experts and communities to shape its future.
NIH HEAL Initiative
The NIH Helping to End Addiction Long-term (HEAL) Initiative is an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis.
NIH Pain Consortium
The NIH Pain Consortium supports initiatives, development of research resources and tools, and hosts events to promote collaboration and highlight advances in pain research across the many NIH Institutes and Centers that address pain.
Rigor & Reproducibility
Information about NINDS effort to encourage rigor, control of bias, and transparency of reporting — important components for all research.