Center for Translation Research and Implementation Science | NHLBI

The Health Inequities and Global Health (HIGH) Branch is NHLBI’s focal point for advancing the scientific understanding of health disparities, minority health, and health inequities and developing implementation strategies for proven interventions that address health disparities and promote health equities around the world.

The Implementation Science Branch (ISB) supports dissemination and implementation research that explores promising strategies for adopting, integrating, sustaining, scaling, and spreading evidence-based heart, lung, blood, and sleep interventions in clinical and public health settings such as clinics, worksites, and communities. This program also supports research training and career development, research mentoring, and research capacity-building and infrastructure development to grow a multidisciplinary heart, lung, blood, and sleep research workforce.

The Translation Research Branch (TRB) leverages methods and insights from late-stage research to expedite the development, testing, and implementation of evidence-based interventions. This includes encouraging the use of methodological innovations (mixed methods approaches, underutilized study designs, etc.), promoting methods for engaging communities and end users in clinical research, designing interventions with the implementation settings in mind, identifying constraints and opportunities for multiple levels of prevention (primary, secondary, and tertiary), testing pragmatic measures with rigorous research methods to support the uptake of interventions, and using data science to leverage multilevel, multisectoral data.

The Office of the Director at CTRIS provides leadership for the Center’s programs and their robust research portfolios, and it is the hub for all late-stage research and dissemination and implementation science across NHLBI. The Office oversees scientific workshops and educational programs about translation, implementation, health inequities, and global health research for trainees and investigators, and it facilitates the assessment and dissemination of health information to the scientific community and the public. The Office also collaborates with others within NHLBI, NIH, other federal health agencies, academia, and global organizations.