Neural Recording and Modulation | BRAIN

These technologies include electrodes, micro/miniscopes, molecular probes for neurotransmitters, magnetothermal tools, bioluminescent recorders, and voltage indicators, as well as supplemental components for these base technologies like custom application specific integrated circuits (ASICs), adaptive optics, and signal processing techniques.

The primary goal of this research is to develop new tools that enable new capabilities for in vivo experiments, including in awake freely moving preparations, at or near cellular resolution, in animal models. Neural activity is defined broadly to include electrical activity, neurotransmitter and neuropeptide signaling, as well as plasticity and intracellular signaling events. The technologies funded through these funding opportunities represent diverse modalities including optical, electrical, magnetic, acoustic and genetic recording/manipulation.

Related Information

For more information on the dissemination of validated tools and resources for basic, translational, or clinical research in BRAIN Initiative-relevant areas, visit the Dissemination page.

For more information about the basic research effort to develop new tools and approaches in support of a more comprehensive mechanistic understanding of the neural basis of behavior, visit the Brain Behavior Quantification and Synchronization program.

For more information about clinical research studies to investigate brain functions, such as sensory perception, motor control, memory, and cognition, visit the Investigative Human Neuroscience page .

For more information on support for clinical trials of invasive devices to treat brain disorders, visit the Therapeutic Human Neuroscience page .