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Gene variant slows form of inherited Alzheimer’s disease
In a family with an inherited form of Alzheimer’s disease, those who carried a gene variant called APOE3Ch had a delay in cognitive impairment and dem...
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Developing treatments for prion diseases
Researchers developed a novel method to turn off prion protein production in mice. The technique could lead to treatments for prion diseases such as m...
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Testing transmission and infection of H5N1 from cows
Researchers found that an H5N1 flu virus from cows could infect mice and ferrets, but airborne transmission wasn’t very efficient.
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March 5, 2024 Edition
Identifying barriers to life-saving diarrhea care
A study in India found that children with diarrhea often aren’t given oral rehydration salts because providers assume that parents prefer other treatments.
Drug cuts risk of allergic reactions to peanuts and other foods
Researchers showed that a drug used to treat allergic asthma can reduce reactions to peanuts and other common foods in children with multiple food allergies.
Insight into mechanisms of ME/CFS
Researchers compared people with post-infectious ME/CFS to those without and found important differences in their brains and other body systems.
February 27, 2024 Edition
SARS-CoV-2 fragments may cause problems after infection
Researchers found that fragments of SARS-CoV-2 left behind after the immune system fights off infection may continue to trigger immune responses.
Blood test may predict psychosis risks
Scientists identified molecules in blood that may reflect a person’s risk for severe psychotic symptoms and future hospitalizations, and may point to personalized treatment options.
Gaps allow substances to move in and out of the brain
Gaps around blood vessels that cross the layers of tissues protecting the brain allow certain cells and molecules to move between the brain and the body.
February 13, 2024 Edition
Understanding sex differences in autoimmune disease
The activity of a type of RNA called Xist may help explain why autoimmune diseases are more common in women than men.
Obesity disrupts mitochondria, reduces fat-burning
Scientists identified a protein that triggers changes in mitochondria that lead to reduced fat-burning to promote weight gain in mice fed a high-fat diet.
How the brain produces speech
Researchers identified how neurons in the human brain encode various elements of speech. The findings might be used to help develop treatments for speech and language disorders.
February 6, 2024 Edition
Comparing side effects after prostate cancer treatment
Men with cancer confined to the prostate experienced different long-term side effects depending on the type of treatment received.
Machine learning identifies federally protected waters
Researchers used machine learning to estimate which waters are protected by the Clean Water Act, which provides the basis for federal regulation of water quality, including water for drinking.
Preventing severe allergic reactions with nanoparticles
Researchers created nanoparticles that could deactivate immune cells and prevent severe allergic reactions in mice.
January 30, 2024 Edition
Research in Context
Diagnosing dementia
This special Research in Context feature explores approaches to the diagnosis of Alzheimer’s and other dementias and the development of strategies to try to prevent their progression.
January 23, 2024 Edition
People taking semaglutide had lower risk of suicidal thoughts
Semaglutide was associated with a lower risk of suicidal thoughts than other anti-obesity and anti-diabetes drugs.
Infections and falls increased in private equity-owned hospitals
After hospitals were purchased by private equity firms, patients had a substantial increase in infections, falls, and other adverse events.
Plastic particles in bottled water
Researchers developed an imaging technique that detected thousands of tiny bits of plastic in common single-use bottles of water.
January 9, 2024 Edition
Anti-diabetes drugs may reduce the risk of colorectal cancer
People with diabetes who took drugs called GLP-1 receptor agonists had a lower risk of colorectal cancer compared with those prescribed other diabetes drugs.
Cochlear nerve damage associated with tinnitus
People with chronic tinnitus were more likely to have signs of damage to their cochlear nerve than people without the condition.
Tracking organ aging and disease
Researchers found that proteins in the blood can be used to track the aging of individual organs, and that faster organ aging increased the risk of disease and death.
December 21, 2023 Edition
2023 NIH Research Highlights - Human Health Advances
NIH accomplishments in disease prevention, diagnosis, and treatment include an antibiotic to prevent sexually transmitted infections, an mRNA vaccine to treat pancreatic cancer, and an app for autism screening.
2023 NIH Research Highlights - Basic Research Insights
Noteworthy NIH advances in basic research include detailed cellular maps of human and nonhuman animal brains, a contraceptive that disables sperm, and a vaccine that could provide broad protection against microbes.
2023 NIH Research Highlights - Promising Medical Findings
NIH findings with potential for enhancing human health include insights into Long COVID and ME/CFS, and a promising blood test for early Alzheimer’s detection.
December 12, 2023 Edition
Deaths associated with pollution from coal power plants
Air pollution from coal power plants was associated with greater mortality than previously thought, but such deaths have decreased due to air pollution regulations and coal power plant retirements.
Impact of COVID-19 infections and vaccines on preterm birth
While contracting COVID-19 increased the risk of preterm birth between 2020 and 2022, the risk then faded, due in large part to SARS-CoV-2 vaccines.
Nanoplastics may help set the stage for Parkinson's risk
Scientists found that tiny plastic particles can enter nerve cells, impair breakdown of structures linked to Parkinson's disease, and harm certain brain regions in mice.