April 22, 2025 Edition

The prevalence of cognitive impairment among older American Indians may be higher than previously thought, according to a new analysis.

Researchers used 3D brain tissue structures called organoids to test a potential therapy for a rare disorder called Timothy syndrome.

A detailed map of all the cells and connections in a single cubic millimeter of the human brain revealed previously unseen aspects of brain structure.

A study of endurance training in rats found molecular changes throughout the body that could help explain the beneficial effects of exercise on health.

In a study of people primarily of European descent, those with two copies of a certain gene, APOE4, predictably began to develop the underlying abnormalities of Alzheimer's disease as early as age 55.

Researchers found that brief bouts of anger can impair the ability of blood vessels to expand and contract, which might have consequences for heart health.

Researchers developed a urine-based test that can distinguish between slow-growing prostate cancers that pose little risk and more aggressive cancers that need treatment.

A single dose of a monoclonal antibody given to children 6 to 10 years of age in Mali proved up to 77% effective at preventing malaria disease.

Researchers found biomarkers in blood that may predict knee osteoarthritis up to eight years before clinical diagnosis.

Researchers found that young children living in areas with more green spaces had fewer symptoms of anxiety and depression.

Synthetic blood platelets stopped bleeding and sped wound healing in animals with internal injuries. The findings suggest they’re likely safe for testing in people.

Scientists uncovered unique structural features of a bitter taste receptor, including a role for cholesterol in receptor activation.

While effective treatments for major depression are available, there is still room for improvement. This special Research in Context feature explores the development of more effective ways to treat depression, including personalized treatment approac...

Researchers pinpointed gut bacteria that affect levels of cholesterol and other compounds linked to heart disease.

Researchers found that depleting certain stem cells improved the immune systems of aged mice.

Researchers developed a wireless implantable device that can monitor bladder filling and emptying in real time and send data to a smartphone.

Researchers found that SARS-CoV-2 can damage heart tissue without directly infecting it.

Scientists identified a specific subtype of bacteria implicated in gum disease that may promote the growth of colorectal tumors.

A study showed that a simple skin biopsy could identify people who had Parkinson's disease or similar disorders with a high degree of accuracy.

Bariatric surgery helped people with type 2 diabetes better control their blood glucose years later compared to medical and lifestyle interventions.

Youth with ADHD have elevated brain activity connecting the frontal cortex with the information processing centers deep in the brain.

Researchers identified a brain circuit that controls vocalization and prevents it from interfering with breathing in mice.

An intervention given to pregnant women by non-specialist providers greatly reduced the chances of developing postpartum depression or anxiety.

Findings about a metabolite of niacin, or vitamin B3, raise concerns about the health effects of too much niacin and suggest new measures to help prevent or treat cardiovascular disease

Researchers designed a synthetic drug that shuts down protein production in a range of different bacteria.